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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T27806 | Lecozotan HCl | SRA-333,SRA333,SRA 333,Lecozotan hydrochloride | 5-HT Receptor |
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. ... | |||
T3826 | Polygalasaponin F | NF-κB , TLR , Akt , PI3K | |
Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po... | |||
T24016 | DPP-4-PIOL | DPP4PIOL | |
DPP-4-PIOL is an antagonist of GABAA. In dentate gyrus granule cells, it acts by selectively antagonizing tonic over phasic GABAergic currents. | |||
T35546 | Yhhu 3792 | ||
Notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes... | |||
T61930 | Yhhu-3792 | ||
Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 enhanced the self-renewal ability of neural stem cells (NSCs), expanded the NSC pool and promoted endogenous neurogenesi... |